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Table 1 Effects of the swelling of feet in rats induced by vinegar-processed RAR (\( \overline{\mathrm{x}} \) ± s, n = 10)

From: Comparison of the acute toxicity, analgesic and anti-inflammatory activities and chemical composition changes in Rhizoma anemones Raddeanae caused by vinegar processing

Group Blank group Model group Methotrexate group RAR group Vinegar-processed RAR group
Dose (mg/kg) 0 0 5 336 336
0.5 h Swell (mm) 4.32 ± 0.50 7.79 ± 0.84 6.83 ± 0.95 7.22 ± 0.45 7.13 ± 0.55
0.5 h Inhibition Rate (%) 0% 80.32% 58.10% 67.13% 65.05%
1.0 h Swell (mm) 4.92 ± 0. 83 8.42 ± 0.56 7.45 ± 0.42 7.41 ± 0.99 7.02 ± 0.23
1.0 h Inhibition Rate (%) 0% 71.13% 51.42% 50.61% 42.68%
2.0 h Swell (mm) 5.21 ± 0. 46 8.57 ± 0.28 7.56 ± 0.25 6.87 ± 0.36* 6.56 ± 0.41*
2.0 h Inhibition Rate (%) 0% 64.49% 45.11% 31.86% 25.91%
3.0 h Swell (mm) 5.13 ± 0.92 8.32 ± 0.39 6.59 ± 0.68* 6.32 ± 0.26** 6.28 ± 0.37**
3.0 h Inhibition Rate (%) 0% 62.18% 28.46% 23.30% 22.42%
4.0 h Swell (mm) 4.97 ± 0. 71 7.95 ± 0.17 6.33 ± 0.48** 6.08 ± 0.78** 6.02 ± 0.21**
4.0 h Inhibition Rate (%) 0% 60.00% 27.36% 22.33% 21.13%
6.0 h Swell (mm) 4.33 ± 0. 19 7.21 ± 0.44 5.02 ± 0.74** 5.30 ± 0.59** 4.98 ± 0.29**
6.0 h Inhibition Rate (%) 0% 66.51% 15.94% 22.40% 15.01%
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