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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation

Fig. 7

Cordyceps miliaris extract suppresses the nuclear translocation of NF-kB (p65) via upregulation of TNF1R expression. a Effect of TNF1R on the nuclear translocation of NF-kB (p65) in CME-treated SKVO-3 cells. b Immunofluorescence micrographs of NF-κB (p65) translocation in SKOV-3 cells. NF-κB (p65) translocation into the nucleus was detected with an anti-NF-κB (p65) antibody (green fluorescence); the inhibition of this signaling pathway is shown by white arrows, whereas activation is indicated with red arrows. Scale bar, 10 μm. Data are presented as means ± standard deviations from triplicate experiments (n = 3). The data represent the mean ± SD from three independent experiments (*p < 0.05, **p < 0.01, and ***p < 0.001)

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