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Table 5 IC50 value of inhibition towards IL-4 and TNF-α release

From: In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds

 IC50 value of inhibition
 IL-4TNF-α
M. oleifera leaf extract2.32 ± 0.08 μg/mL1.20 ± 0.29 μg/mL
M. oleifera seed extract4.28 ± 0.05 μg/mL2.52 ± 0.33 μg/mL
M. oleifera pod extract2.74 ± 0.17 μg/mL2.52 ± 0.15 μg/mL
Ethyl-(E)–undec-6-enoate (1)16.91 ± 0.56 μM9.90 ± 2.31 μM
3,5,6-trihydroxy-2-(2,3,4,5,6-pentahydroxyphenyl)-4H-chromen-4-one (2)12.17 ± 0.13 μM6.45 ± 0.26 μM
Quercetin (3)10.42 ± 0.07 μM6.24 ± 0.31 μM
Kaempferol (4)14.55 ± 3.24 μM8.73 ± 0.59 μM
β-sitosterol-3-O-glucoside (5)7.33 ± 1.76 μM5.26 ± 0.00 μM
Oleic acid (6)8.10 ± 0.26 μM10.11 ± 1.49 μM
Glucomoringin (7)7.59 ± 0.39 μM3.86 ± 8.26 μM
Stigmasterol (9)10.99 ± 1.57 μM6.05 ± 16.54 μM
Ketotifen fumarate (positive control)3.08 ± 0.49 μg/mL
(7.24 ± 1.16 μM)
2.91 ± 0.33 μg/mL
(6.85 ± 0.77 μM)