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Table 4 IC50 values of inhibition towards beta-hexosaminidase and histamine release

From: In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds

 IC50 values of inhibition
 Beta-hexosaminidaseHistamine
M. oleifera leaf extract7.17 ± 1.69 μg/mL**11.66 ± 1.26 μg/mL
M. oleifera seed extract10.68 ± 0.63 μg/mL5.97 ± 0.84 μg/mL
M. oleifera pod extract14.89 ± 1.25 μg/mL7.43 ± 1.01 μg/mL
Ethyl-(E)–undec-6-enoate (1)82.68 ± 1.98 μM82.07 ± 13.75 μM
3,5,6-trihydroxy-2-(2,3,4,5,6-pentahydroxyphenyl)-4H-chromen-4-one (2)17.70 ± 23.29 μM44.87 ± 2.13 μM
Quercetin (3)19.07 ± 7.19 μM*7.77 ± 27.86 μM
Kaempferol (4)29.39 ± 6.26 μM46.94 ± 10.26 μM
β-sitosterol-3-O-glucoside (5)24.93 ± 2.10 μM
Oleic acid (6)53.76 ± 8.95 μM56.05 ± 37.11 μM
Glucomoringin (7)10.43 ± 1.51 μM*27.22 ± 18.62 μM
Stigmasterol (9)75.92 ± 4.66 μM38.27 ± 24.48 μM
Ketotifen fumarate (positive control)15.19 ± 1.10 μg/mL
(35.70 ± 2.59 μM)
6.97 ± 0.04 μg/mL
(16.38 ± 0.10 μM)