Fig. 5From: Tong-Xie-Yao-Fang improves intestinal permeability in diarrhoea-predominant irritable bowel syndrome rats by inhibiting the NF-κB and notch signalling pathwaysTXYF inhibits the activation of NF-κB and regulates the production of pro-inflammatory cytokines in colonic tissues of IBS-D rats. a qRT-PCR detection for IL-1β, IL-6, TNF-α and KC in colonic tissues. b Western blot analysis for p-p65 and P65 in colonic tissues. aP < 0.05 vs the blank group. bP < 0.05 vs the model group. cP > 0.05 vs the rifaximin groupBack to article page