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Table 4 IC50 values (μg/mL) of ROS inhibitory activity of tested samples on human whole blood and PMNs

From: Standardized ethanol extract, essential oil and zerumbone of Zingiber zerumbet rhizome suppress phagocytic activity of human neutrophils

Samples

Zymosan

PMA

Whole blood

PMNs

Whole blood

PMNs

Z. zerumbet extract (ZZE)

6.49 ± 2.16

2.89 ± 0.98

10.87 ± 1.50

14.87 ± 2.70***

Z. zerumbet essential oil (ZZEO)

8.71 ± 1.37*

5.88 ± 1.70

11.63 ± 1.78

12.62 ± 0.87**

Zerumbone (ZER)

8.25 ± 0.73*

(37.77 ± 3.38)

6.83 ± 0.68

(31.25 ± 3.10)

3.79 ± 0.24

(17.36 ± 1.08)

Aspirin

2.63 ± 0.17

(14.57 ± 0.92)

1.95 ± 0.07

(10.82 ± 0.40)

7.65 ± 0.43

(42.46 ± 2.40)

2.94 ± 0.26

(16.30 ± 1.46)

  1. Data are presented as (mean ± SEM, n = 3). Data were analyzed by one-way ANOVA followed by Dunnet’s post hoc test. IC50 values in μM are shown in parentheses. Significance of differences with respect to control: *p < 0.05, ** p < 0.01, ***p < 0.001