Fig. 8From: Mulberry leaf reduces inflammation and insulin resistance in type 2 diabetic mice by TLRs and insulin Signalling pathwayDownstream transcription factors’ expression interfered with WEM in diabetic mice. An evident decrease in MyD88 was detected after the treatment. According to the downstream transcription factor TRAF6 activation with WEM in diabetic mice, a profound decrease in TRAF6 was shown after the treatment. According to the downstream transcription factor NF-κB p65 activation with WEM in diabetic mice, NF-κB p65 expression showed a huge reduction after the treatment. Normalized results are expressed as means ± SEM (n = 3). *P < 0.05, **P < 0.01, NC mice vs. Diabetic mice; #P < 0.05, ##P < 0.01, WEM vs. Diabetic miceBack to article page