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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Alkaloid extract of Corydalis yanhusuo inhibits angiogenesis via targeting vascular endothelial growth factor receptor signaling

Fig. 5

Schematic diagram of effects of Alkaloid extract of YHS on Angiogenesis Alkaloid extract of YHS exerted anti-angiogenic effect on HUVECs by attenuating the activation of VEGF/VEGFR2 signaling pathway and its downstream mediators including AKT, ERK and STAT3. The blocked VEGF/VEGFR2 signaling by alkaloid extract of YHS lead to decreased proliferation, migration and tube formation of endothelial cells

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