Fig. 5From: Alkaloid extract of Corydalis yanhusuo inhibits angiogenesis via targeting vascular endothelial growth factor receptor signalingSchematic diagram of effects of Alkaloid extract of YHS on Angiogenesis Alkaloid extract of YHS exerted anti-angiogenic effect on HUVECs by attenuating the activation of VEGF/VEGFR2 signaling pathway and its downstream mediators including AKT, ERK and STAT3. The blocked VEGF/VEGFR2 signaling by alkaloid extract of YHS lead to decreased proliferation, migration and tube formation of endothelial cellsBack to article page