TY - JOUR AU - Carmeliet, P. AU - Jain, R. K. PY - 2011 DA - 2011// TI - Molecular mechanisms and clinical applications of angiogenesis JO - Nature. VL - 473 UR - https://doi.org/10.1038/nature10144 DO - 10.1038/nature10144 ID - Carmeliet2011 ER - TY - JOUR AU - Losordo, D. W. AU - Dimmeler, S. PY - 2004 DA - 2004// TI - Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines JO - Circulation. VL - 109 UR - https://doi.org/10.1161/01.CIR.0000128595.79378.FA DO - 10.1161/01.CIR.0000128595.79378.FA ID - Losordo2004 ER - TY - JOUR AU - Scaldaferri, F. AU - Vetrano, S. AU - Sans, M. AU - Arena, V. AU - Straface, G. AU - Stigliano, E. AU - Repici, A. AU - Sturm, A. AU - Malesci, A. AU - Panes, J. PY - 2009 DA - 2009// TI - VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis JO - Gastroenterology. VL - 136 UR - https://doi.org/10.1053/j.gastro.2008.09.064 DO - 10.1053/j.gastro.2008.09.064 ID - Scaldaferri2009 ER - TY - JOUR AU - Lamalice, L. AU - Boeuf, F. AU - Huot, J. PY - 2007 DA - 2007// TI - Endothelial cell migration during angiogenesis JO - Circ Res VL - 100 UR - https://doi.org/10.1161/01.RES.0000259593.07661.1e DO - 10.1161/01.RES.0000259593.07661.1e ID - Lamalice2007 ER - TY - JOUR AU - Eilken, H. M. AU - Adams, R. H. PY - 2010 DA - 2010// TI - Dynamics of endothelial cell behavior in sprouting angiogenesis JO - Curr Opin Cell Biol VL - 22 UR - https://doi.org/10.1016/j.ceb.2010.08.010 DO - 10.1016/j.ceb.2010.08.010 ID - Eilken2010 ER - TY - JOUR AU - Weis, S. M. AU - Cheresh, D. A. PY - 2011 DA - 2011// TI - Tumor angiogenesis: molecular pathways and therapeutic targets JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2537 DO - 10.1038/nm.2537 ID - Weis2011 ER - TY - JOUR AU - Vasudev, N. S. AU - Reynolds, A. R. PY - 2014 DA - 2014// TI - Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions JO - Angiogenesis. VL - 17 UR - https://doi.org/10.1007/s10456-014-9420-y DO - 10.1007/s10456-014-9420-y ID - Vasudev2014 ER - TY - JOUR AU - Koch, S. AU - Claesson-Welsh, L. PY - 2012 DA - 2012// TI - Signal transduction by vascular endothelial growth factor receptors JO - Cold Spring Harbor perspectives in medicine VL - 2 UR - https://doi.org/10.1101/cshperspect.a006502 DO - 10.1101/cshperspect.a006502 ID - Koch2012 ER - TY - JOUR AU - Fontanella, C. AU - Ongaro, E. AU - Bolzonello, S. AU - Guardascione, M. AU - Fasola, G. AU - Aprile, G. PY - 2014 DA - 2014// TI - Clinical advances in the development of novel VEGFR2 inhibitors JO - Annals of translational medicine VL - 2 ID - Fontanella2014 ER - TY - JOUR AU - Meadows, K. N. AU - Bryant, P. AU - Pumiglia, K. PY - 2001 DA - 2001// TI - Vascular endothelial growth factor induction of the angiogenic phenotype requires Ras activation JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M108069200 DO - 10.1074/jbc.M108069200 ID - Meadows2001 ER - TY - JOUR AU - Chen, T. T. AU - Luque, A. AU - Lee, S. AU - Anderson, S. M. AU - Segura, T. AU - Iruela-Arispe, M. L. PY - 2010 DA - 2010// TI - Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells JO - J Cell Biol VL - 188 UR - https://doi.org/10.1083/jcb.200906044 DO - 10.1083/jcb.200906044 ID - Chen2010 ER - TY - JOUR AU - Cantley, L. C. PY - 2002 DA - 2002// TI - The phosphoinositide 3-kinase pathway JO - Science. VL - 296 UR - https://doi.org/10.1126/science.296.5573.1655 DO - 10.1126/science.296.5573.1655 ID - Cantley2002 ER - TY - JOUR AU - Chen, S. AU - Murphy, D. AU - Lassoued, W. AU - Thruston, G. AU - Feldman, M. AU - Lee, W. PY - 2008 DA - 2008// TI - Activated STAT3 is a mediator and biomarker of VEGF endothelial activation JO - Cancer Biol Ther VL - 7 UR - https://doi.org/10.4161/cbt.7.12.6967 DO - 10.4161/cbt.7.12.6967 ID - Chen2008 ER - TY - JOUR AU - Bhattacharya, S. AU - Ray, R. M. AU - Johnson, L. R. PY - 2005 DA - 2005// TI - STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells JO - The Biochemical journal VL - 392 UR - https://doi.org/10.1042/BJ20050465 DO - 10.1042/BJ20050465 ID - Bhattacharya2005 ER - TY - JOUR AU - Lu, J. AU - Zhang, K. AU - Nam, S. AU - Anderson, R. A. AU - Jove, R. AU - Wen, W. PY - 2010 DA - 2010// TI - Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling JO - Carcinogenesis. VL - 31 UR - https://doi.org/10.1093/carcin/bgp292 DO - 10.1093/carcin/bgp292 ID - Lu2010 ER - TY - JOUR AU - Xia, Y. AU - Song, X. AU - Li, D. AU - Ye, T. AU - Xu, Y. AU - Lin, H. AU - Meng, N. AU - Li, G. AU - Deng, S. AU - Zhang, S. PY - 2014 DA - 2014// TI - YLT192, a novel, orally active bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy in preclinical models JO - Sci Rep VL - 4 UR - https://doi.org/10.1038/srep06031 DO - 10.1038/srep06031 ID - Xia2014 ER - TY - JOUR AU - Elice, F. AU - Rodeghiero, F. PY - 2010 DA - 2010// TI - Bleeding complications of antiangiogenic therapy: pathogenetic mechanisms and clinical impact JO - Thromb Res VL - 125 ID - Elice2010 ER - TY - JOUR AU - Fan, M. AU - Zhang, J. AU - Wang, Z. AU - Wang, B. AU - Zhang, Q. AU - Zheng, C. AU - Li, T. AU - Ni, C. AU - Wu, Z. AU - Shao, Z. PY - 2014 DA - 2014// TI - Phosphorylated VEGFR2 and hypertension: potential biomarkers to indicate VEGF-dependency of advanced breast cancer in anti-angiogenic therapy JO - Breast Cancer Res Treat VL - 143 UR - https://doi.org/10.1007/s10549-013-2793-6 DO - 10.1007/s10549-013-2793-6 ID - Fan2014 ER - TY - JOUR AU - Liao, D. AU - Wang, P. AU - Jia, C. AU - Sun, P. AU - Qi, J. AU - Zhou, L. AU - Li, X. PY - 2016 DA - 2016// TI - Identification and developmental expression profiling of putative alkaloid biosynthetic genes in Corydalis yanhusuo bulbs JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep19460 DO - 10.1038/srep19460 ID - Liao2016 ER - TY - JOUR AU - Wang, L. AU - Zhang, Y. AU - Wang, Z. AU - Gong, N. AU - Kweon, T. D. AU - Vo, B. AU - Wang, C. AU - Zhang, X. AU - Chung, J. Y. AU - Alachkar, A. PY - 2016 DA - 2016// TI - The Antinociceptive properties of the Corydalis yanhusuo extract JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0162875 DO - 10.1371/journal.pone.0162875 ID - Wang2016 ER - TY - JOUR AU - Ling, H. AU - Wu, L. AU - Li, L. PY - 2006 DA - 2006// TI - Corydalis yanhusuo rhizoma extract reduces infarct size and improves heart function during myocardial ischemia/reperfusion by inhibiting apoptosis in rats JO - Phytother Res VL - 20 UR - https://doi.org/10.1002/ptr.1875 DO - 10.1002/ptr.1875 ID - Ling2006 ER - TY - JOUR AU - Xu, Z. AU - Chen, X. AU - Zhang, Q. AU - Chen, L. AU - Wang, Y. PY - 2011 DA - 2011// TI - Corydalis yanhusuo W.T. Wang extract inhibits MCF-7 cell proliferation by inducing cell cycle G2/M arrest JO - The American journal of Chinese medicine VL - 39 UR - https://doi.org/10.1142/S0192415X11009044 DO - 10.1142/S0192415X11009044 ID - Xu2011 ER - TY - JOUR AU - Gao, J. L. AU - Shi, J. M. AU - He, K. AU - Zhang, Q. W. AU - Li, S. P. AU - Lee, S. M. AU - Wang, Y. T. PY - 1994 DA - 1994// TI - Yanhusuo extract inhibits metastasis of breast cancer cells by modulating mitogen-activated protein kinase signaling pathways JO - Oncol Rep VL - 20 ID - Gao1994 ER - TY - JOUR AU - Yan, J. J. AU - He, X. AU - Feng, S. AU - Zhai, Y. R. AU - Ma, Y. T. AU - Liang, S. AU - Jin, C. H. PY - 2014 DA - 2014// TI - Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo JO - BMC Complement Altern Med VL - 14 UR - https://doi.org/10.1186/1472-6882-14-306 DO - 10.1186/1472-6882-14-306 ID - Yan2014 ER - TY - JOUR AU - Wei, X. AU - Shen, H. AU - Wang, L. AU - Meng, Q. AU - Liu, W. PY - 2016 DA - 2016// TI - Analyses of Total alkaloid extract of Corydalis yanhusuo by comprehensive RP x RP liquid chromatography with pH difference JO - Journal of analytical methods in chemistry VL - 2016 UR - https://doi.org/10.1155/2016/9752735 DO - 10.1155/2016/9752735 ID - Wei2016 ER - TY - JOUR AU - Woolkalis, M. J. AU - DeMelfi, T. M. AU - Blanchard, N. AU - Hoxie, J. AU - Brass, L. F. PY - 1995 DA - 1995// TI - Regulation of thrombin receptors on human umbilical vein endothelial cells JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.17.9868 DO - 10.1074/jbc.270.17.9868 ID - Woolkalis1995 ER - TY - JOUR AU - Zhou, W. AU - Tang, W. AU - Sun, Z. AU - Li, Y. AU - Dong, Y. AU - Pei, H. AU - Peng, Y. AU - Wang, J. AU - Shao, T. AU - Jiang, Z. PY - 2016 DA - 2016// TI - Discovery and optimization of N-substituted 2-(4-pyridinyl) thiazole carboxamides against tumor growth through regulating angiogenesis signaling pathways JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep33434 DO - 10.1038/srep33434 ID - Zhou2016 ER - TY - JOUR AU - Zhu, Z. AU - Zhao, Y. AU - Li, J. AU - Tao, L. AU - Shi, P. AU - Wei, Z. AU - Sheng, X. AU - Shen, D. AU - Liu, Z. AU - Zhou, L. PY - 2016 DA - 2016// TI - Cryptotanshinone, a novel tumor angiogenesis inhibitor, destabilizes tumor necrosis factor-alpha mRNA via decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR JO - Mol Carcinog VL - 55 UR - https://doi.org/10.1002/mc.22383 DO - 10.1002/mc.22383 ID - Zhu2016 ER - TY - JOUR AU - Mattagajasingh, S. N. AU - Yang, X. P. AU - Irani, K. AU - Mattagajasingh, I. AU - Becker, L. C. PY - 2012 DA - 2012// TI - Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein kinase C JO - Biochim Biophys Acta VL - 1823 UR - https://doi.org/10.1016/j.bbamcr.2012.02.008 DO - 10.1016/j.bbamcr.2012.02.008 ID - Mattagajasingh2012 ER - TY - JOUR AU - Zhao, Y. AU - Zhang, D. AU - Wang, S. AU - Tao, L. AU - Wang, A. AU - Chen, W. AU - Zhu, Z. AU - Zheng, S. AU - Gao, X. AU - Lu, Y. PY - 2013 DA - 2013// TI - Holothurian glycosaminoglycan inhibits metastasis and thrombosis via targeting of nuclear factor-kappaB/tissue factor/factor Xa pathway in melanoma B16F10 cells JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0056557 DO - 10.1371/journal.pone.0056557 ID - Zhao2013 ER - TY - JOUR AU - Feflea, S. AU - Cimpean, A. M. AU - Ceausu, R. A. AU - Gaje, P. AU - Raica, M. PY - 2012 DA - 2012// TI - Effects of antibodies to EG-VEGF on angiogenesis in the chick embryo chorioallantoic membrane JO - In vivo VL - 26 ID - Feflea2012 ER - TY - JOUR AU - Ahmad, S. AU - Ullah, F. AU - Ayaz, M. AU - Zeb, A. AU - Ullah, F. AU - Sadiq, A. PY - 2016 DA - 2016// TI - Antitumor and anti-angiogenic potentials of isolated crude saponins and various fractions of Rumex hastatus D JO - Don Biological research VL - 49 UR - https://doi.org/10.1186/s40659-016-0079-2 DO - 10.1186/s40659-016-0079-2 ID - Ahmad2016 ER - TY - JOUR AU - Ayaz, M. AU - Junaid, M. AU - Ullah, F. AU - Sadiq, A. AU - Subhan, F. AU - Khan, M. A. AU - Ahmad, W. AU - Ali, G. AU - Imran, M. AU - Ahmad, S. PY - 2016 DA - 2016// TI - Molecularly Characterized Solvent Extracts and Saponins from Polygonum hydropiper L. Show High Anti-Angiogenic, Anti-Tumor, Brine Shrimp, and Fibroblast NIH/3T3 Cell Line Cytotoxicity JO - Frontiers in pharmacology VL - 7 UR - https://doi.org/10.3389/fphar.2016.00074 DO - 10.3389/fphar.2016.00074 ID - Ayaz2016 ER - TY - JOUR AU - Corre, I. AU - Paris, F. AU - Huot, J. PY - 2017 DA - 2017// TI - The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells JO - Oncotarget. VL - 8 UR - https://doi.org/10.18632/oncotarget.18264 DO - 10.18632/oncotarget.18264 ID - Corre2017 ER - TY - JOUR AU - Shen, K. AU - Ji, L. AU - Lu, B. AU - Wang, Z. PY - 2012 DA - 2012// TI - C-Jun N-terminal kinase mediated VEGFR2 sustained phosphorylation is critical for VEGFA-induced angiogenesis in vitro and in vivo JO - Cell Biochem Biophys VL - 64 UR - https://doi.org/10.1007/s12013-012-9363-0 DO - 10.1007/s12013-012-9363-0 ID - Shen2012 ER - TY - JOUR AU - Folkman, J. PY - 2007 DA - 2007// TI - Angiogenesis: an organizing principle for drug discovery? JO - Nat Rev Drug Discov VL - 6 UR - https://doi.org/10.1038/nrd2115 DO - 10.1038/nrd2115 ID - Folkman2007 ER - TY - JOUR AU - Shibuya, M. PY - 2011 DA - 2011// TI - Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: a crucial target for anti- and pro-Angiogenic therapies JO - Genes & cancer VL - 2 UR - https://doi.org/10.1177/1947601911423031 DO - 10.1177/1947601911423031 ID - Shibuya2011 ER - TY - JOUR AU - Kamba, T. AU - McDonald, D. M. PY - 2007 DA - 2007// TI - Mechanisms of adverse effects of anti-VEGF therapy for cancer JO - Br J Cancer VL - 96 UR - https://doi.org/10.1038/sj.bjc.6603813 DO - 10.1038/sj.bjc.6603813 ID - Kamba2007 ER - TY - JOUR AU - Martins, G. G. AU - Kolega, J. PY - 2006 DA - 2006// TI - Endothelial cell protrusion and migration in three-dimensional collagen matrices JO - Cell Motil Cytoskeleton VL - 63 UR - https://doi.org/10.1002/cm.20104 DO - 10.1002/cm.20104 ID - Martins2006 ER - TY - JOUR AU - Nacev, B. A. AU - Liu, J. O. PY - 2011 DA - 2011// TI - Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin a and itraconazole JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0024793 DO - 10.1371/journal.pone.0024793 ID - Nacev2011 ER - TY - JOUR AU - Kowanetz, M. AU - Ferrara, N. PY - 2006 DA - 2006// TI - Vascular endothelial growth factor signaling pathways: therapeutic perspective JO - Clin Cancer Res VL - 12 UR - https://doi.org/10.1158/1078-0432.CCR-06-1520 DO - 10.1158/1078-0432.CCR-06-1520 ID - Kowanetz2006 ER - TY - JOUR AU - Takahashi, H. AU - Shibuya, M. PY - 2005 DA - 2005// TI - The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions JO - Clin Sci VL - 109 UR - https://doi.org/10.1042/CS20040370 DO - 10.1042/CS20040370 ID - Takahashi2005 ER - TY - JOUR AU - Wu, X. AU - Xu, H. AU - Wu, Z. AU - Chen, C. AU - Liu, J. AU - Wu, G. AU - Yao, X. AU - Liu, F. AU - Li, G. AU - Shen, L. PY - 2015 DA - 2015// TI - Formononetin, a novel FGFR2 inhibitor, potently inhibits angiogenesis and tumor growth in preclinical models JO - Oncotarget. VL - 6 ID - Wu2015 ER - TY - JOUR AU - Cargnello, M. AU - Roux, P. P. PY - 2011 DA - 2011// TI - Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases JO - Microbiol Mol Biol Rev VL - 75 UR - https://doi.org/10.1128/MMBR.00031-10 DO - 10.1128/MMBR.00031-10 ID - Cargnello2011 ER -