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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Heracleum moellendorffii roots inhibit the production of pro-inflammatory mediators through the inhibition of NF-κB and MAPK signaling, and activation of ROS/Nrf2/HO-1 signaling in LPS-stimulated RAW264.7 cells

Fig. 1

Inhibitory effect of HM-R against NO and PGE2 production in LPS-stimulated RAW264.7 cells. a and b RAW264.7 cells were pretreated with HM-R for 2 h and then co-treated with LPS (1 μg/ml) for 18 h. NO and PGE2 production was measured by Griess assay and Prostaglandin E2 ELISA Kit, respectively. c RAW264.7 cells were pretreated with HM-R or TA for 2 h and then co-treated with LPS (1 μg/ml) for 18 h. NO production was measured by Griess assay. d RAW264.7 cells were treated with HM-R for 24 h. Cell viability was measured by MTT assay. *P < 0.05 compared to the cells without the treatment, and #P < 0.05 compared to the cells treated with LPS alone

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