Fig. 2

Effects of AS-IV on metabolic parameters in kidney damage rats. a Fasting blood glucose was recorded every week after injecting STZ two weeks. b Body weight (b), Blood urea nitrogen (c), Scr serum creatinine (d), proteinuria (e), HbA1c (f) of rats was measured at the end of the study. g Kidney sections from each group of rats were detected by HE and PAS staining, bar = 100 μm. H Representative images of TUNEL staining, bar = 50 μm. Data are expressed as mean ± SD (n = 6). ****p < 0.0001, ***p < 0.001 vs. control; ###p < 0.001 vs. DN, ##p < 0.01; %p < 0.05 vs DN + ING-4w. &&p < 0.01, &p < 0.05