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Fig. 9 | BMC Complementary and Alternative Medicine

Fig. 9

From: Immuno-enhancement effects of Platycodon grandiflorum extracts in splenocytes and a cyclophosphamide-induced immunosuppressed rat model

Fig. 9

Effect of PGE on immunity-associated spleen and thymus damage in CP-induced immunosuppressed rats. Rats were given saline, CP (5 mg/kg/day), and PGE (0, 10, 30, or 100 mg/kg/day) once daily for 28 days, after which damage in the spleen (a) and thymus (b) was analyzed histologically. Representative images of the sectioned spleens of (a) normal rats (saline treatment), (b) control rats (treated with only CP), and (c–e) CP and PGE-treated rats [(c) 10 mg/kg, (d) 30 mg/kg, or (e) 100 mg/kg PGE]. Scale bar = 100 μm. CV, central vein; LN, lymph nodule; MZ, marginal zone; RP, red pulp; C, cortex; M, medulla

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