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Table 2 GO biological process terms of tanshinones modules display partially

From: Mechanism of tanshinones and phenolic acids from Danshen in the treatment of coronary heart disease based on co-expression network

Modules

GO terms

P-value

Module 1

response to chemical stimulus

1.64 × 10−25

Module 2

regulation of cellular protein metabolic process

5.07 × 10−15

Module 3

G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

3.86 × 10−11

Module 4

positive regulation of cellular process

1.23 × 10−14

Module 5

DNA strand elongation involved in DNA replication

9.21 × 10−31

Module 6

histone deubiquitination

1.25 × 10−17

Module 7

DNA metabolic process

3.76 × 10−13

Module 8

T cell receptor signaling pathway

4.80 × 10−24

regulation of T cell activation

4.77 × 10− 19

Module 9

growth hormone receptor signaling pathway

1.65 × 10−13

Module 10

double-strand break repair

7.40 × 10− 18

Module 11

lipid metabolic process

6.71 × 10− 6

Module 12

transcription from RNA polymerase II promoter

2.63 × 10−7

Module 13

lipid oxidation

6.42 × 10−9

Module 14

positive regulation of catalytic activity

7.76 × 10−10

Module 15

histone acetylation

1.91 × 10−6

Module 16

nucleic acid metabolic process

4.33 × 10−6

Module 17

cell division

2.83 × 10− 6

Module 18

DNA repair

2.79 × 10−10

Module 19

M/G1 transition of mitotic cell cycle

6.21 × 10−13

Module 20

enzyme linked receptor protein signaling pathway

2.07 × 10−7

Module 21

positive regulation of cellular process

1.46 × 10−5

Module 22

positive regulation of immune response

1.37 × 10−4

activation of immune response

7.48 × 10−5

Module 23

ethanol oxidation

1.19 × 10−6

Module 24

cellular component disassembly involved in execution phase of apoptosis

2.33 × 10−10

Module 25

histone lysine methylation

3.01 × 10−8

Module 26

enzyme linked receptor protein signaling pathway

5.33 × 10−6

Module 27

regulation of fatty acid beta-oxidation

3.30 × 10−6

Module 28

blood circulation

1.38 × 10−5

blood coagulation

5.26 × 10−5

Module 29

regulation of chromosome condensation

1.31 × 10−4

Module 30

regulation of lipoprotein lipase activity

8.15 × 10−6

Module 31

G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

6.95 × 10−7

Module 32

negative regulation of histone modification

6.83 × 10−6

Module 33

regulation of T cell activation

1.93 × 10−8

regulation of immune response

7.63 × 10−7

Module 34

G1 phase of mitotic cell cycle

1.06 × 10−5

Module 35

virus-host interaction

4.31 × 10−8

Module 36

heterochromatin maintenance

1.31 × 10−4

Module 37

double-strand break repair via nonhomologous end joining

2.99 × 10−6

Module 38

G-protein coupled receptor signaling pathway

3.78 × 10−7

Module 39

chromatin organization

4.23 × 10−5