Fig. 7

Effect of curcumin on protein expressions of TAK1, JNK and p38 in PF rats. a Representative immunoblots of p-TAK1, p-JNK, p-p38 and GAPDH in PF rats of each group were shown. After induction of PF, the protein levels of p-TAK1 (b), p-JNK (c) and p-p38 (d) were significantly increased. Curcumin markedly reduced protein levels of p-TAK1, p-JNK and p-p38 at moderate (20 mg/kg) and high (40 mg/kg) doses in PF rats. ANOVA was performed and followed with Tukey’s post hoc test. ***P < 0.001 vs. control group; ##P < 0.01, ###P < 0.001 vs. PF group