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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Curcumin ameliorates peritoneal fibrosis via inhibition of transforming growth factor-activated kinase 1 (TAK1) pathway in a rat model of peritoneal dialysis

Fig. 3

Effect of curcumin on the expressions of TGF-β1 in peritoneum of experimental PF model. TGF-β1-positive cells were occasionally found in the peritoneum of the control group (a), but were increased in the PF group (b). Curcumin at 10 mg/kg (c), 20 mg/kg (d) and 40 mg/kg (e) all markedly reduced the number of TGF-β1-positive cells. f Quantification analysis of number of TGF-β1-positive cells in the peritoneum (cells/mm2) in each group. g Quantitative real-time PCR showed the TGF-β1 mRNA expression in the peritoneum of each group. ANOVA was performed and followed with Tukey’s post hoc test. ***P < 0.001 vs. control group; ##P < 0.01, ###P < 0.001 vs. PF group

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