Fig. 1

Effects of Curcumin on the peritoneal thickness of PF rats. Peritoneum was stained with Masson’s trichrome to measure the thickness of submesothelial zone. Representative photomicrographs of peritoneal samples was shown. a Control rats showed a thin submesothelial layer of peritoneum, without any morphological changes. b PF rats showed a marked thickening of the submesothelial compact zone. Curcumin prevented the thickening of submesothelial zone with low (c), moderate (d) and high (e) doses. d Quantification analysis of the effect of curcumin on peritoneal thickness. Bar, 100 μm. Magnification, 200×. Data are represented as means ± SD for 12 rat of each group. ANOVA was performed and followed with Tukey’s post hoc test. ***P < 0.001 vs. control group; ###P < 0.001 vs. PF group