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Table 6 Percent AChE and BChE inhibition potential of pyrogallol, morin and rutin isolated from Bergenia ciliata rhizome

From: Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities

Samples Concentrations (μg/mL) AChE percent inhibition (mean ± S.E.M) AChE IC50 (μg/mL) BChE percent inhibition (mean ± S.E.M) BChE IC50 (μg/mL)
Pyrogallol 1000 94.35 ± 0.72 ns   92.02 ± 1.89 ns  
500 87.40 ± 1.51 ns   80.35 ± 0.30 *  
250 80.12 ± 0.62 ns 28 71.18 ± 1.38 ns 70
125 66.24 ± 2.14 ns   58.28 ± 0.93 ns  
Morin 1000 85.51 ± 3.19***   80.46 ± 0.76***  
500 77.23 ± 0.91***   68.44 ± 2.22***  
250 68.82 ± 0.80 *** 64 60.51 ± 0.50*** 116
125 56.33 ± 1.45 ***   51.13 ± 0.56***  
Rutin 1000 75.11 ± 1.41***   72.05 ± 0.86***  
500 66.72 ± 0.62***   62.47 ± 1.72***  
250 60.20 ± 2.35*** 118 56.68 ± 0.70*** 172
125 48.09 ± 0.64***   45.00 ± 3.79***  
Galanthamine 1000 97.24 ± 0.74   92.26 ± 0.92  
500 90.43 ± 0.50   86.51 ± 0.77  
250 79.00 ± 0.65 24 71.80 ± 0.48 54
125 66.07 ± 1.46   62.43 ± 0.39  
  1. Galanthamine was used as a positive control. Data is represented as (mean ± S.E.M) n = 3. Values significantly different as compared to positive control, *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: P > 0.05