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Table 4 Cytotoxicity, antiviral effect, and selectivity index of medicinal herb extracts

From: Investigation of Brassica juncea, Forsythia suspensa, and Inula britannica: phytochemical properties, antiviral effects, and safety

Materials

CC50a (μg/mL)

EC50b (μg/mL)

SIc

 Tamiflu

569.25 ± 13.43

1.72 ± 0.21

330.170

 Chlorogenic acid

72.34 ± 2.21

24.77 ± 1.03

2.920

 Kaempferol

18.63 ± 0.06

2.46 ± 0.21

7.585

Plants

Extract Solvents

CC50 (mg/mL)

EC50 (mg/mL)

SI

 Brassica juncea

Ethanol

1.91 ± 0.11

Not effective

Not effective

Water

9.73 ± 1.40

0.71 ± 0.06

13.668

 Forsythia suspensa

Ethanol

0.02 ± 0.00

Not effective

Not effective

Water

0.10 ± 0.02

Not effective

Not effective

 Inula britannica

Ethanol

0.19 ± 0.02

Not effective

Not effective

Water

0.68 ± 0.11

Not effective

Not effective

  1. aCC50, 50% cell cytotoxicity concentration
  2. bEC50, 50% virus-inhibitory concentration
  3. cSI, selectivity index (CC50/EC50)
  4. Experiments were conducted in triplicate