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Table 4 Cytotoxic potential of A. jacquemontii extracts against DU-145 prostate cancer, HL-60 human leukemia cell lines

From: Phytochemical, in-vitro biological and chemo-preventive profiling of Arisaema jacquemontii Blume tuber extracts

Sample code

DU-145

HL-60

% survival at 20 μg/mL

ED 50 μg/mL

% survival at 20 μg/mL

ED50 μg/mL

n-Hex

98.2 ± 2.1

45.11

92.6 ± 0.8

55.2

CHCl3

68.7 ± 1.5

N/A

52.8 ± 1.7

N/A

Ace

85.3 ± 0.8

N/A

58.1 ± 0.6

N/A

EtOAc

88.2 ± 1.9

52.2

50.6 ± 1.2

N/A

EtOH

45 ± 0.5

N/A

66.2 ± 1.4

N/A

MeOH

89.4 ± 1.5

66.24

86.7 ± 0.8

65.3

EtOH+ CHCl3

75.6 ± 1.6

N/A

54.2 ± 0.9

N/A

MeOH+ CHCl3

66.3 ± 0.8

N/A

71.4 ± 0.3

N/A

Ace + EtOAc

45.6 ± 1.7

N/A

25.7 ± 1.4

N/A

EtOH+ EtOAc

23.2 ± 0.7

N/A

60.7 ± 0.8

N/A

MeOH+ EtOAc

22.7 ± 1.4

N/A

54.4 ± 0.7

N/A

  1. All data means showed in triplicate. ± means standard error
  2. ED 50 = concentration at 50% inhibition
  3. Taxol used as a positive control
  4. N/A not active
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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