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Table 4 Cytotoxic potential of A. jacquemontii extracts against DU-145 prostate cancer, HL-60 human leukemia cell lines

From: Phytochemical, in-vitro biological and chemo-preventive profiling of Arisaema jacquemontii Blume tuber extracts

Sample code DU-145 HL-60
% survival at 20 μg/mL ED 50 μg/mL % survival at 20 μg/mL ED50 μg/mL
n-Hex 98.2 ± 2.1 45.11 92.6 ± 0.8 55.2
CHCl3 68.7 ± 1.5 N/A 52.8 ± 1.7 N/A
Ace 85.3 ± 0.8 N/A 58.1 ± 0.6 N/A
EtOAc 88.2 ± 1.9 52.2 50.6 ± 1.2 N/A
EtOH 45 ± 0.5 N/A 66.2 ± 1.4 N/A
MeOH 89.4 ± 1.5 66.24 86.7 ± 0.8 65.3
EtOH+ CHCl3 75.6 ± 1.6 N/A 54.2 ± 0.9 N/A
MeOH+ CHCl3 66.3 ± 0.8 N/A 71.4 ± 0.3 N/A
Ace + EtOAc 45.6 ± 1.7 N/A 25.7 ± 1.4 N/A
EtOH+ EtOAc 23.2 ± 0.7 N/A 60.7 ± 0.8 N/A
MeOH+ EtOAc 22.7 ± 1.4 N/A 54.4 ± 0.7 N/A
  1. All data means showed in triplicate. ± means standard error
  2. ED 50 = concentration at 50% inhibition
  3. Taxol used as a positive control
  4. N/A not active