Groups
|
Days
|
Inhibition of platelet aggregation (%)
|
---|
AA (500 μg/mL)
|
ADP (20 μmol/L)
|
Collagen (10 μg/mL)
|
Epinephrine (300 μmol/L)
|
---|
Control
|
30
|
69.54 ± 8.12
|
41.54 ± 3.24
|
20.74 ± 1.54
|
14.65 ± 0.88
|
60
|
76.12 ± 7.58
|
41.66 ± 3.68
|
20.65 ± 0.89
|
14.24 ± 0.97
|
SCD1
|
30
|
65.29 ± 6.21*
|
36.66 ± 0.54*
|
20.41 ± 0.75
|
13.45 ± 1.24
|
60
|
57.55 ± 7.08*
|
37.80 ± 0.87*
|
17.54 ± 1.12*
|
13.20 ± 1.54*
|
SCD2
|
30
|
60.89 ± 6.29**
|
35.37 ± 0.70*
|
18.80 ± 0.98
|
13.98 ± 0.95
|
60
|
52.06 ± 5.98**
|
33.65 ± 1.21*
|
16.99 ± 2.54*
|
13.00 ± 0.84*
|
Aspirin
|
30
|
43.44 ± 8.45**
|
30.45 ± 0.98**
|
12.87 ± 1.23**
|
12.59 ± 1.05*
|
60
|
46.87 ± 8.99**
|
26.76 ± 1.25**
|
12.33 ± 1.01**
|
12.98 ± 0.90*
|
- n = 10, Average values ± SEM;
- SCD1: S. cumini dose 1; 150 mg/kg; SCD2: S. cumini dose 2; 500 mg/kg
- *p ≤ 0.05 significant as compared to control; **p ≤ 0.005 highly significant as compared to control
- AA Arachidonic acid, ADP Adenosine diphosphate