Fig. 2

GAG production by cartilage explants (n = 8 pigs) conditioned with simulated biological extract of turmeric (3, 9 or 15 μg/mL; TUR1, TUR3 and TUR5 respectively) compared with simulated biological extract containing no turmeric (C) in the presence (Panel a) or absence (Panel b) of lipopolysaccharide (LPS; 5 μg/mL) (+). Explants were cultured for a total of 96 h and were conditioned with TUR for the first 48 h prior to exposure to LPS. Data are shown for the final 48 h only. * denotes significant change from baseline within treatments. Letters denote significant differences between treatments at specific time points