Fig. 1
From: Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell
Effect of BBR on MDA-MB-231 viability and LDH release. Cells were seeded in 96-well plates at 5000 cells per well and treated with various concentrations of BBR for 48 h, the control wells were treated with equivalent amount of medium alone. The effect of BBR on MDA-MB-231 (a) viability and (b) LDH release was determined by the assays described in the Methods section. The relative cell viability and LDH leakage was calculated as the ratio of the absorbance at 490 nm of each treatment group against those of the corresponding untreated control group. Each value represents the mean ± S.D. (n = 6) of three independent experiments. * p < 0.05, ** p < 0.01, compared to the control