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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

Fig. 6

Alterations of proteins and mRNAs such as GFAP, EAAT1, EAAT2, and NeuN in the PFC of mice induced by CUMS as well as XYS and Flu treatment. a Expression of GFAP protein in the PFC. b Expression of EAAT1 protein in the PFC. c Expression of EAAT2 protein in the PFC. d Expression of NeuN protein in the PFC. e Expression of GFAP mRNA in the PFC. f Expression of EAAT1 mRNA in the PFC. g Expression of EAAT2 mRNA in the PFC. h Expression of NeuN mRNA in the PFC. The Nemenyi method was used for comparative analysis of the real-time PCR data of GFAP and EAAT1 and the Western blot data of EAAT2 between groups. Values are presented as medians and interquartile ranges. Then, Sidak’s method was used for comparative analysis of real-time PCR data of EAAT2 and NeuN and Western blot data of GFAP, EAAT1 and NeuN between groups. Values are presented as the mean ± SEM (n = 5), *P < 0.05, **P < 0.01 versus the control group; #P < 0.05, ##P < 0.01 versus the CUMS group

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