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Table 2 COG functional classification of proteins identified in Fraction 2

From: Royal jelly-derived proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro scratch wound model

Protein ID

Identity

E value

COG gene ID

COG num

Functional description

Functional class

Class description

A0A088A2A5

0.62

8.00E-51

YP_875383

COG0048

Ribosomal protein S12

J

Translation, ribosomal structure and biogenesis;

A0A088A2I2

0.64

0

YP_003548756

COG1004

UDP-glucose 6-dehydrogenase

M

Cell wall/membrane/envelope biogenesis;

A0A088A2L4

0.43

0

YP_634186

COG0326

Molecular chaperone, HSP90 family

O

Posttranslational modification, protein turnover, chaperones;

A0A088A3F4

0.32

1.00E-05

YP_002346601

COG1530

Ribonuclease G or E

J

Translation, ribosomal structure and biogenesis;

A0A088A461

0.3

3.00E-17

YP_001958455

COG1196

Chromosome segregation ATPase

D

Cell cycle control, cell division, chromosome partitioning;

A0A088A5A6

0.41

6.00E-37

YP_001737337

COG1100

GTPase SAR1 family domain

R

General function prediction only;

A0A088A5X7

0.34

1.00E-159

YP_001736560

COG0480

Translation elongation factor EF-G, a GTPase

J

Translation, ribosomal structure and biogenesis;

A0A088A6D6

0.52

8.00E-69

YP_422148

COG0852

NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)

C

Energy production and conversion;

A0A088A6T4

0.64

0

YP_742173

COG1053

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

C

Energy production and conversion;

A0A088A7D1

0.38

1.00E-34

YP_001737337

COG1100

GTPase SAR1 family domain

R

General function prediction only;

A0A088A8F0

0.49

1.00E-113

YP_004484975

COG5257

Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)

J

Translation, ribosomal structure and biogenesis;

A0A088A9V8

0.67

1.00E-178

YP_004616696

COG1089

GDP-D-mannose dehydratase

M

Cell wall/membrane/envelope biogenesis;

A0A088ADQ6

0.6

2.00E-47

YP_686965

COG0100

Ribosomal protein S11

J

Translation, ribosomal structure and biogenesis;

A0A088AEV2

0.46

2.00E-29

NP_579542

COG0198

Ribosomal protein L24

J

Translation, ribosomal structure and biogenesis;

A0A088AFM4

0.48

0

YP_004483987

COG1222

ATP-dependent 26S proteasome regulatory subunit

O

Posttranslational modification, protein turnover, chaperones;

A0A087EPB0

0.72

0

YP_007414867

COG0206

Cell division GTPase FtsZ

D

Cell cycle control, cell division, chromosome partitioning;

A0A087EQE2

0.76

0

NP_814529

COG0192

S-adenosylmethionine synthetase

H

Coenzyme transport and metabolism;

A0A088AFT2

0.37

5.00E-19

YP_001737450

COG2125

Ribosomal protein S6E (S10)

J

Translation, ribosomal structure and biogenesis;

A0A088AGJ8

0.5

0

NP_927210

COG0443

Molecular chaperone DnaK (HSP70)

O

Posttranslational modification, protein turnover, chaperones;

A0A088AJ01

0.3

6.00E-24

YP_008152560

COG0515

Serine/threonine protein kinase

T

Signal transduction mechanisms;

A0A088AJJ6

0.42

1.00E-105

YP_003640197

COG0513

Superfamily II DNA and RNA helicase

L

Replication, recombination and repair;

A0A088AMB8

0.81

0

YP_004357703

COG0055

FoF1-type ATP synthase, beta subunit

C

Energy production and conversion;

A0A088AN20

0.84

6.00E-39

YP_004089966

COG5272

Ubiquitin

O

Posttranslational modification, protein turnover, chaperones;

A0A088ANZ0

0.54

0

NP_276090

COG1155

Archaeal/vacuolar-type H + -ATPase catalytic subunit A/Vma1

C

Energy production and conversion;

A0A088ARA9

0.38

5.00E-07

YP_006863204

COG4352

Ribosomal protein L13E

J

Translation, ribosomal structure and biogenesis;

A0A088ATI7

0.34

8.00E-27

YP_008431664

COG1100

GTPase SAR1 family domain

R

General function prediction only;

A0A0B4J2L4

0.5

1.00E-123

NP_070800

COG1222

ATP-dependent 26S proteasome regulatory subunit

O

Posttranslational modification, protein turnover, chaperones;

A0A0B4J2N0

0.52

1.00E-127

NP_614161

COG1222

ATP-dependent 26S proteasome regulatory subunit

O

Posttranslational modification, protein turnover, chaperones;

A0A0B4J2P2

0.54

1.00E-125

NP_275871

COG1222

ATP-dependent 26S proteasome regulatory subunit

O

Posttranslational modification, protein turnover, chaperones;

A0A1Q1N6G0

0.28

1.00E-17

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

D3JZ08

0.37

2.00E-16

YP_001538809

COG1158

Transcription termination factor Rho

K

Transcription;

D3Y5T0

0.3

4.00E-25

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

A0A087EQF2

0.77

0

YP_007414230

COG0362

6-phosphogluconate dehydrogenase

G

Carbohydrate transport and metabolism;

A0A087ZMS7

0.34

9.00E-19

YP_002463522

COG1100

GTPase SAR1 family domain

R

General function prediction only;

O18330

0.28

9.00E-20

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

O77061

0.28

1.00E-17

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

Q4ZJX1

0.3

3.00E-21

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

Q6IMJ9

0.3

2.00E-20

YP_004643033

COG3386

Sugar lactone lactonase YvrE

G

Carbohydrate transport and metabolism;

V5 T859

0.79

0

YP_003986273

COG0057

Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

G

Carbohydrate transport and metabolism;

W8S9B2

0.37

3.00E-70

YP_003266114

COG5277

Actin-related protein

Z

Cytoskeleton;

A0A087ZMT8

0.63

3.00E-13

YP_008432142

COG0638

20S proteasome, alpha and beta subunits

O

Posttranslational modification, protein turnover, chaperones;

A0A087ZNX0

0.35

1.00E-29

YP_008431664

COG1100

GTPase SAR1 family domain

R

General function prediction only;

A0A087ZQ27

0.51

0

YP_001369341

COG0443

Molecular chaperone DnaK (HSP70)

O

Posttranslational modification, protein turnover, chaperones;

A0A087ZQI5

0.73

0

YP_423504

COG0056

FoF1-type ATP synthase, alpha subunit

C

Energy production and conversion;

A0A087ZR05

0.35

1.00E-17

YP_008797954

COG1310

Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif

O

Posttranslational modification, protein turnover, chaperones;

A0A087ZRA1

0.37

1.00E-93

YP_003266114

COG5277

Actin-related protein

Z

Cytoskeleton;

A0A087ZRE3

0.55

0

YP_003669641

COG5256

Translation elongation factor EF-1alpha (GTPase)

J

Translation, ribosomal structure and biogenesis;

A0A087ZUL8

0.51

8.00E-43

YP_003650076

COG0185

Ribosomal protein S19

J

Translation, ribosomal structure and biogenesis;

A0A087ZV06

0.41

8.00E-14

YP_001030947

COG2007

Ribosomal protein S8E

J

Translation, ribosomal structure and biogenesis;

A0A087ZV73

0.33

9.00E-30

YP_008431664

COG1100

GTPase SAR1 family domain

R

General function prediction only;

A0A087ZW54

0.57

1.00E-166

YP_001995997

COG0050

Translation elongation factor EF-Tu, a GTPase

J

Translation, ribosomal structure and biogenesis;

A0A087ZW88

0.35

3.00E-60

YP_007146068

COG3325

Chitinase, GH18 family

G

Carbohydrate transport and metabolism;

A0A087ZZN8

0.42

4.00E-62

YP_003434754

COG0638

20S proteasome, alpha and beta subunits

O

Posttranslational modification, protein turnover, chaperones;

  1. MRJPs and the predicted functions are in bold typeface