Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms

Table 1 Information on 17 hub targets

Uniprot ID	Gene symbol	Protein name	Degree
P04637	TP53	Cellular tumor antigen p53	71
P05412	JUN	Transcription factor AP-1	68
P31749	AKT1	RAC-alpha serine/threonine-protein kinase	67
P05231	IL6	Interleukin-6	64
P01375	TNF	Tumor necrosis factor	62
P15692	VEGFA	Vascular endothelial growth factor A	61
P00533	EGFR	Epidermal growth factor receptor	60
P42574	CASP3	Caspase 3	59
P28482	MAPK1	Mitogen-activated protein kinase 1	59
P10415	BCL2	Apoptosis regulator Bcl-2	59
P45983	MAPK8	Mitogen-activated protein kinase 8	59
P35354	PTGS2	Prostaglandin G/H synthase 2	59
P01133	EGF	Pro-epidermal growth factor	58
P01106	MYC	Myc proto-oncogene protein	57
P14780	MMP9	Matrix metalloproteinase-9	57
P01100	FOS	Proto-oncogene c-Fos	55
P01137	TGFB1	Transforming growth factor beta-1	51

ISSN: 2662-7671