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Table 5 Effect of cisplatin (CP) and different treatments of AHE on cardiac tissue protein, oxidative stress markers and lipid peroxidation

From: Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

Group Protein (μg/mg Tissue) H2O2 (nM/min/mg Tissue) Nitrite content (NO μM/ml) MDA (nM/min/mg protein)
Control 1.638 ± 0.033 1.932 ± 0.015 42.59 ± 0.552 2.874 ± 0.180
CP 1.061 ± 0.075*** 5.975 ± 0.025*** 75.72 ± 0.707*** 7.711 ± 0.264***
AHE alone 1.614 ± 0.015+++ 1.911 ± 0.049+++ 41.72 ± 0.650+++ 2.859 ± 0.086+++
CP + AHE 1.419 ± 0.028*,+++ 5.016 ± 0.013***,+++ 62.63 ± 0.765***,+++ 5.774 ± 0.285***,+++,###
AHE + CP 1.536 ± 0.032+++ 2.794 ± 0.005**,+++ 49.93 ± 0.419**,+++ 3.219 ± 0.189+++
CP + Sily 1.564 ± 0.019+++ 2.717 ± 0.006**,+++ 50.60 ± 0.322**,+++ 3.225 ± 0.112+++
  1. Data are represented mean ± S.E.M (n = 6). Asterisks *, **, *** indicates p < 0.05, 0.001, 0.0001 vs. control; +, ++, +++ indicates p < 0.05, 0.001, 0.0001 vs. CP alone; #, ##, ### indicates p < 0.05, 0.001, 0.0001 vs. AHE + CP. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)