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Table 4 Effect of cisplatin (CP) and different treatments of AHE on cardiac enzymatic antioxidant levels and GSH profile

From: Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

Group GSH (μM/g tissue) GR (nM/min/mg protein) GST (nM/min/mg protein) γ-GT (nM/min/mg Protein) GPx (nM/min/mg Protein)
Control 20.55 ± 0.280 154.9 ± 0.958 148.6 ± 0.665 303.5 ± 0.811 122.4 ± 0.639
CP 12.41 ± 0.278*** 111.8 ± 1.569*** 110.9 ± 1.002*** 100.6 ± 0.947*** 66.77 ± 0.924***
AHE alone 20.66 ± 0.236+++ 155.6 ± 0.439+++ 148.4 ± 0.816+++ 306.9 ± 0.401+++ 122.9 ± 0.285+++
CP + AHE 14.34 ± 0.23***,++,### 121.6 ± 1.086***,+++,### 123.9 ± 1.110***,+++,### 189.3 ± 0.559***,+++,### 81.51 ± 1.659***,+++,###
AHE + CP 18.43 ± 0.415**,### 147.3 ± 0.948**,+++ 141.7 ± 0.60**,+++ 293.9 ± 0.602**,+++ 111.7 ± 0.602***,+++
CP + Sily 18.33 ± 0.293**,### 146.0 ± 1.055**,+++ 141.0 ± 0.899**,+++ 294.7 ± 0.999**,+++ 115.1 ± 1.00**,+++
  1. Data are represented mean ± S.E.M (n = 6). Asterisks *, **, *** indicates p < 0.05, 0.001, 0.0001 vs. control; +, ++, +++ indicates p < 0.05, 0.001, 0.0001 vs. CP alone; #, ##, ### indicates p < 0.05, 0.001, 0.0001 vs. AHE + CP. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)