Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

Table 2 Effect of DOX and/or AHE treatment on body weight, heart weight and heart /body weight ratio of rats

Treatment (mg/kg)	Body weight (BW)(g)		Heart weight (HW)(g)	Ratio (HW/BWx10³)
Treatment (mg/kg)	Initial	Final
Control	218.0 ± 1.065	259.7 ± 1.202	0.692 ± 0.03	2.66
CP	220.0 ± 1.56	226.0 ± 1.033^***	0.502 ± 0.034^**	2.22
AHE alone	219.5 ± 1.02	260.0 ± 1.07⁺⁺⁺	0.699 ± 0.025⁺⁺⁺	2.68
CP + AHE	220.5 ± 1.06	244.0 ± 1.15^***,+++	0.592 ± 0.013^*,#	2.42
AHE + CP	220.3 ± 0.882	256.3 ± 1.14^+++,###	0.690 ± 0.024^b**	2.69
Sily + CP	222.0 ± 0.577	256.5 ± 922^b	0.691 ± 0.019^b**	2.69

Data are represented mean ± S.E.M (n = 6). Asterisks ^{*, **, ***} indicates p < 0.05, 0.001, 0.0001 vs. control; ^{+, ++, +++} indicates p < 0.05, 0.001, 0.0001 vs. CP alone; ^{#, ##, ###} indicates p < 0.05, 0.001, 0.0001 vs. AHE + CP. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters. (One way ANOVA followed by Tukey’s multiple comparison tests). Sily-Silymarin

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