| |
Control
|
GLES1
|
GLES2
|
GLES3
|
|---|
|
Female
|
Male
|
Female
|
Male
|
Female
|
Male
|
Female
|
Male
|
|---|
|
CHOL (mg/dL)
|
72.97 ± 5.41
|
63.71 ± 3.47
|
69.88 ± 3.47
|
55.21 ± 3.09
|
84.17 ± 6.18
|
44.02 ± 1.54***
|
91.51 ± 4.63*
|
44.40 ± 2.70***
|
|
TG (mg/dL)
|
30.12 ± 3.47
|
19.69 ± 1.93
|
38.61 ± 6.18
|
14.67 ± 1.16*
|
28.57 ± 3.09
|
11.97 ± 1.16***
|
28.96 ± 3.09
|
9.65 ± 0.77***
|
|
HDL-C (mg/dL)
|
52.90 ± 3.47
|
20.85 ± 4.25
|
49.42 ± 2.32
|
22.39 ± 3.86
|
61.78 ± 4.63
|
14.29 ± 3.47
|
67.95 ± 3.47*
|
19.31 ± 4.25
|
|
LDL-C (mg/dL)
|
6.95 ± 2.32
|
33.98 ± 3.47
|
4.25 ± 1.54
|
26.25 ± 2.70
|
9.65 ± 2.70
|
24.32 ± 3.09
|
10.42 ± 1.54
|
20.46 ± 2.70**
|
|
VLDLC (mg/dL)
|
6.02 ± 0.69
|
3.94 ± 0.35
|
7.68 ± 1.27
|
2.90 ± 0.23*
|
5.75 ± 0.66
|
2.39 ± 0.19***
|
5.79 ± 0.58
|
1.89 ± 0.12***
|
|
CRR
|
1.37 ± 0.018
|
4.45 ± 0.80
|
1.41 ± 0.02
|
3.45 ± 0.67
|
1.37 ± 0.02
|
4.88 ± 0.88
|
1.35 ± 0.02
|
3.53 ± 0.69
|
|
CRI-2
|
0.12 ± 0.03
|
2.81 ± 0.69
|
0.09 ± 0.03
|
2.04 ± 0.59
|
0.14 ± 0.04
|
3.30 ± 0.77
|
0.15 ± 0.02
|
2.18 ± 0.62
|
|
AC
|
0.37 ± 0.02
|
3.44 ± 0.80
|
0.41 ± 0.02
|
2.45 ± 0.67
|
0.37 ± 0.02
|
3.88 ± 0.88
|
0.35 ± 0.02
|
2.53 ± 0.69
|
|
AIP
|
−0.263 ± 0.061
|
0.058 ± 0.089
|
−0.147 ± 0.051
|
−0.115 ± 0.083
|
−0.346 ± 0.073
|
0.019 ± 0.010
|
−0.382 ± 0.051
|
−0.210 ± 0.097
|
- n = 10 rats/sex/group; data are presented as mean ± SEM
- *indicates significant difference (p < 0.05) compared to the control
- **indicates significant difference (p < 0.01) compared to the control
- ***indicates significant difference (p < 0.001) compared to the control
