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Table 6 Packed cell volume, rectal temperature and body weight of infected mice treated with 80% methanol extract of the leaves of Olea europaea in prophylactic test

From: Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Groups Packed cell volume Rectal temperature Body weight
D 0 D3 % change D0 D3 % change D0 D3 % change
2% TW80 58.56 ± 0.38 56.47 ± 0.38 −3.57 36.10 ± 0.14 35.20 ± 0.14 −2.49 28.35 ± 0.40 27.65 ± 0.39 −2.45
CQ25 mg/kg 58.70 ± 0.65 58.59 ± 0.67 −0.19a3 35.81 ± 0.22 35.74 ± 0.20 0.22a3 28.77 ± 0.38 28.87 ± 0.38 0.36a3
200 mg/kg 58.65 ± 0.49 57.3 ± 0.48 −2.30a3b3d1e2 36.06 ± 0.12 35.30 ± 0.11 −2.08b3d2e2 28.76 ± 0.38 28.09 ± 0.38 −2.32b3
400 mg/kg 59.10 ± 0.49 57.91 ± 0.47 −2.01a3b3 36.40 ± 0.14 35.86 ± 0.13 −1.50a3b3 29.04 ± 0.34 28.40 ± 0.35 −2.20a1b3
600 mg/kg 58.70 ± 0.66 57.56 ± 0.67 −1.91a3b3 36.07 ± 0.13 35.71 ± 0.13 −1.00a3b3 28.86 ± 0.55 28.24 ± 0.53 −2.13a2b3
  1. Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine, D0 pre-inoculation value on day 0, D3 post- treatment value on day 3 after inoculation