Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Table 5 Parasitemia and survival time of infected mice treated with 80% methanol extract of the leaves of Olea europaea in prophylactic test

Groups	% Parasitemia	% Suppression	Survival time (days)
2% TW80	20.95 ± 0.27	–	6.33 ± 0.21
CQ25 mg/kg	4.7 ± 0.17	77.53^a3	12.50 ± 0.22^a3
200 mg/kg	16.87 ± 0.23	19.32^a3b3d3e3	7.33 ± 0.21^a1b3d2e3
400 mg/kg	15.17 ± 0.23	27.47^a3b3e1	8.67 ± 0.21^a3b3
600 mg/kg	14.08 ± 0.11	32.69^a3b3	9.17 ± 0.17^a3b3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine

ISSN: 2662-7671