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Table 4 Packed cell volume, rectal temperature and body weight of infected mice treated with 80% methanol extract of the leaves of Olea europaea in Rane’s test

From: Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Groups Packed cell volume Rectal temperature Body weight
D3 D7 % change D3 D7 % change D3 D7 % change
2% TW80 51.86 ± 0.53 43.20 ± 0.36 −16.69 35.36 ± 0.17 33.51 ± 0.13 −5.25 28.43 ± 0.72 25.70 ± 0.74 −9.65
CQ25 mg/kg 50.31 ± 0.42 51.84 ± 0.35 3.05a3 35.18 ± 0.11 35.47 ± 0.13 0.83a3 28.63 ± 0.61 29.07 ± 0.63 1.51a3
200 mg/kg 51.93 ± 0.59 46.62 ± 0.63 −10.23a3b3d2e3 35.31 ± 0.25 33.71 ± 0.24 −4.52a1b3d1e3 27.00 ± 0.60 24.71 ± 0.64 −8.50b3
400 mg/kg 51.84 ± 0.68 47.86 ± 0.70 −7.68a3b3 35.36 ± 0.09 34.05 ± 0.13 −3.72a3b3 28.22 ± 0.49 26.04 ± 0.46 −7.71a2b3
600 mg/kg 51.78 ± 0.43 48.26 ± 0.53 −6.81a3b3 35.36 ± 0.07 34.23 ± 0.06 −3.18a3b3 27.63 ± 0.49 25.59 ± 0.50 −3.39a2b3
  1. Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine, D3 pre-treatment value on day 3, D4 post- treatment value on day 7