Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Table 3 Parasitemia and survival time of infected mice treated with 80% methanol extract of the leaves of Olea europaea in Rane’s test

Groups	% Parasitemia	% Suppression	Survival time (days)
2% TW80	71.67 ± 0.79	–	7.66 ± 0.21
CQ25 mg/kg	0.00 ± 0.00	100.00^a3	28.00 ± 0.00^a3
200 mg/kg	51.55 ± 0.71	28.08^a3b3d3e3	11.16 ± 0.30^a3b3d1e3
400 mg/kg	41.23 ± 0.64	42.77^a3b3e3	12.50 ± 0.34^a3b3e2
600 mg/kg	36.73 ± 0.35	48.75^a3b3	14.17 ± 0.31^a3b3

Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine

ISSN: 2662-7671