Skip to main content

Table 2 Packed cell volume, rectal temperature and body weight of infected mice treated with 80% methanol extract of the leaves of Olea europaea in the 4-day suppressive test

From: Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

Groups Packed cell volume Rectal temperature Body weight
D0 D4 % change D0 D4 % change D0 D4 % change
2% TW80 61.81 ± 1.16 56.19 ± 1.09 −9.09 36.74 ± 0.06 34.8 ± 0.18 −5.28 28.25 ± 0.41 26.93 ± 0.41 −4.66
CQ25 mg/kg 61.52 ± 1.13 61.20 ± 1.12 −0.52a3 35.52 ± 0.27 35.51 ± 0.20 −0.03a3 28.93 ± 0.34 29.26 ± 0.37 1.13a3
200 mg/kg 59.61 ± 0.68 56.60 ± 0.77 −5.05a3b3d3e3 36.23 ± 0.20 34.96 ± 0.17 −3.50a2b3e2 28.95 ± 0.32 27.79 ± 0.35 −4.00b3
400 mg/kg 62.08 ± 0.77 60.15 ± 0.73 −3.10a3b3 36.46 ± 0.17 35.67 ± 0.22 −2.16a3b2 29.03 ± 0.49 28.05 ± 0.47 −3.39a2b3
600 mg/kg 62.05 ± 0.65 60.51 ± 0.67 −2.49a3b3 36.00 ± 0.18 35.56 ± 0.16 −1.22a3 28.02 ± 0.74 27.16 ± 0.79 −3.06a2b3
  1. Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine, D0 pre-treatment value on day 0, D4 post- treatment value on day 4