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Table 4 Morphometric analysis of organs in BALB/c mice treated with RHTR

From: Biological and toxicological evaluation of Rhus trilobata Nutt. (Anacardiaceae) used traditionally in mexico against cancer

Time Treatment Measurement Kidney Heart Lung Spleen Liver
24 h AE W 0.36 ± 0.04 (1.4%) 0.13 ± 0.02 (0.5%) 0.22 ± 0.02 (0.8%) 0.11 ± 0.01 (0.4%) 1.44 ± 0.2 (5.5%)
D 9.23 ± 0.5 8.8 ± 0.45 * 11.04 ± 1.4 14.5 ± 1.16 29.6 ± 0.96
FF W 0.37 ± 0.04 (1.5%) 0.12 ± 0.01 (0.5%) 0.22 ± 0.05 (0.9%) 0.10 ± 0.03 * (0.4%) 1.36 ± 0.3 (5.4%)
D 10.17 ± 0.8 8.42 ± 0.64 11.6 ± 0.42 15.1 ± 1.8 26.1 ± 2.96
1X PBS W 0.35 ± 0.06 (1.4%) 0.12 ± 0.02 (0.5%) 0.23 ± 0.03 (0.9%) 0.13 ± 0.02 (0.5%) 1.3 ± 0.21 (5.4%)
D 10.06 ± 0.5 8.19 ± 1.2 11.94 ± 1.1 14.1 ± 2.12 27.9 ± 1.2
14 days AE W 0.37 ± 0.01 (1.3%) 0.16 ± 0.02 (0.5%) 0.26 ± 0.02 (0.9%) 0.11 ± 0.01 (0.4%) 1.29 ± 0.09 (4.5%)
D 10.3 ± 0.55 9.5 ± 1.7 13.74 ± 0.9 17.4 ± 1.15 28.6 ± 4.83
FF W 0.22 ± 0.14 (0.8%) 0.17 ± 0.02 (0.6%) 0.28 ± 0.05 (0.9%) 0.14 ± 0.01 * (0.5%) 1.48 ± 0.15 (5.3%)
D 10.34 ± 0.4 9.35 ± 0.14 13.93 ± 1.7 17.01 ± 0.6 30.5 ± 0.86
1X PBS W 0.35 ± 0.05 (1.3%) 0.16 ± 0.03 (0.6%) 0.21 ± 0.01 (0.8%) 0.12 ± 0.01 (0.5%) 1.35 ± 0.12 (5.1%)
D 10.8 ± 0.6 10.03 ± 0.8 14.6 ± 2.95 15.2 ± 1.4 31.8 ± 3.3
  1. The results show the mean ± S.D. of two biological replicates (n = 5)
  2. Measurement of W: weight (g), D: larger diameter (mm) and (% ROW): relative organ weight, for each organ
  3. *, p < 0.05 vs control values without treatment (1X PBS)
  4. AE aqueous extract, FF flavonoid fraction