Time | Treatment | Measurement | Kidney | Heart | Lung | Spleen | Liver |
---|---|---|---|---|---|---|---|
24 h | AE | W | 0.36 ± 0.04 (1.4%) | 0.13 ± 0.02 (0.5%) | 0.22 ± 0.02 (0.8%) | 0.11 ± 0.01 (0.4%) | 1.44 ± 0.2 (5.5%) |
D | 9.23 ± 0.5 | 8.8 ± 0.45 * | 11.04 ± 1.4 | 14.5 ± 1.16 | 29.6 ± 0.96 | ||
FF | W | 0.37 ± 0.04 (1.5%) | 0.12 ± 0.01 (0.5%) | 0.22 ± 0.05 (0.9%) | 0.10 ± 0.03 * (0.4%) | 1.36 ± 0.3 (5.4%) | |
D | 10.17 ± 0.8 | 8.42 ± 0.64 | 11.6 ± 0.42 | 15.1 ± 1.8 | 26.1 ± 2.96 | ||
1X PBS | W | 0.35 ± 0.06 (1.4%) | 0.12 ± 0.02 (0.5%) | 0.23 ± 0.03 (0.9%) | 0.13 ± 0.02 (0.5%) | 1.3 ± 0.21 (5.4%) | |
D | 10.06 ± 0.5 | 8.19 ± 1.2 | 11.94 ± 1.1 | 14.1 ± 2.12 | 27.9 ± 1.2 | ||
14 days | AE | W | 0.37 ± 0.01 (1.3%) | 0.16 ± 0.02 (0.5%) | 0.26 ± 0.02 (0.9%) | 0.11 ± 0.01 (0.4%) | 1.29 ± 0.09 (4.5%) |
D | 10.3 ± 0.55 | 9.5 ± 1.7 | 13.74 ± 0.9 | 17.4 ± 1.15 | 28.6 ± 4.83 | ||
FF | W | 0.22 ± 0.14 (0.8%) | 0.17 ± 0.02 (0.6%) | 0.28 ± 0.05 (0.9%) | 0.14 ± 0.01 * (0.5%) | 1.48 ± 0.15 (5.3%) | |
D | 10.34 ± 0.4 | 9.35 ± 0.14 | 13.93 ± 1.7 | 17.01 ± 0.6 | 30.5 ± 0.86 | ||
1X PBS | W | 0.35 ± 0.05 (1.3%) | 0.16 ± 0.03 (0.6%) | 0.21 ± 0.01 (0.8%) | 0.12 ± 0.01 (0.5%) | 1.35 ± 0.12 (5.1%) | |
D | 10.8 ± 0.6 | 10.03 ± 0.8 | 14.6 ± 2.95 | 15.2 ± 1.4 | 31.8 ± 3.3 |