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Table 4 Morphometric analysis of organs in BALB/c mice treated with RHTR

From: Biological and toxicological evaluation of Rhus trilobata Nutt. (Anacardiaceae) used traditionally in mexico against cancer

Time

Treatment

Measurement

Kidney

Heart

Lung

Spleen

Liver

24 h

AE

W

0.36 ± 0.04 (1.4%)

0.13 ± 0.02 (0.5%)

0.22 ± 0.02 (0.8%)

0.11 ± 0.01 (0.4%)

1.44 ± 0.2 (5.5%)

D

9.23 ± 0.5

8.8 ± 0.45 *

11.04 ± 1.4

14.5 ± 1.16

29.6 ± 0.96

FF

W

0.37 ± 0.04 (1.5%)

0.12 ± 0.01 (0.5%)

0.22 ± 0.05 (0.9%)

0.10 ± 0.03 * (0.4%)

1.36 ± 0.3 (5.4%)

D

10.17 ± 0.8

8.42 ± 0.64

11.6 ± 0.42

15.1 ± 1.8

26.1 ± 2.96

1X PBS

W

0.35 ± 0.06 (1.4%)

0.12 ± 0.02 (0.5%)

0.23 ± 0.03 (0.9%)

0.13 ± 0.02 (0.5%)

1.3 ± 0.21 (5.4%)

D

10.06 ± 0.5

8.19 ± 1.2

11.94 ± 1.1

14.1 ± 2.12

27.9 ± 1.2

14 days

AE

W

0.37 ± 0.01 (1.3%)

0.16 ± 0.02 (0.5%)

0.26 ± 0.02 (0.9%)

0.11 ± 0.01 (0.4%)

1.29 ± 0.09 (4.5%)

D

10.3 ± 0.55

9.5 ± 1.7

13.74 ± 0.9

17.4 ± 1.15

28.6 ± 4.83

FF

W

0.22 ± 0.14 (0.8%)

0.17 ± 0.02 (0.6%)

0.28 ± 0.05 (0.9%)

0.14 ± 0.01 * (0.5%)

1.48 ± 0.15 (5.3%)

D

10.34 ± 0.4

9.35 ± 0.14

13.93 ± 1.7

17.01 ± 0.6

30.5 ± 0.86

1X PBS

W

0.35 ± 0.05 (1.3%)

0.16 ± 0.03 (0.6%)

0.21 ± 0.01 (0.8%)

0.12 ± 0.01 (0.5%)

1.35 ± 0.12 (5.1%)

D

10.8 ± 0.6

10.03 ± 0.8

14.6 ± 2.95

15.2 ± 1.4

31.8 ± 3.3

  1. The results show the mean ± S.D. of two biological replicates (n = 5)
  2. Measurement of W: weight (g), D: larger diameter (mm) and (% ROW): relative organ weight, for each organ
  3. *, p < 0.05 vs control values without treatment (1X PBS)
  4. AE aqueous extract, FF flavonoid fraction