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Table 1 Effect of hydro-alcoholic extract of A. lacucha (HEBA) in formalin-induced nociception test

From: Antinociceptive activities of Artocarpus lacucha Buch-ham (Moraceae) and its isolated phenolic compound, catechin, in mice

Treatment Dose (mg/Kg) Nociceptive response (s) Edema thickness (mm) % inhibition
Early Phase (0–10 min) % inhibition Late Phase (11–45 min) % inhibition
Vehicle 113.56 ± 1.82 407.21 ± 5.46 1.45 ± 0.07
Morphine 5 22.59 ± 2.27* 80.11 28.33 ± 2.43* 93.04 0.78 ± 0.06** 45.93
HEBA 50 66.73 ± 9.43* 41.24 167.34 ± 9.61* 58.91 1.10 ± 0.03* 24.00
HEBA 100 50.87 ± 1.96* 55.21 122.45 ± 8.78* 69.93 0.94 ± 0.06* 35.31
HEBA 200 34.59 ± 0.65* 69.54 106.80 ± 4.05* 73.77 0.85 ± 0.07* 41.10
  1. Data are presented as mean ± SEM (n = 5). HEBA = hydro-methanolic extract of A. lacucha bark. * and ** represents p < 0.001 and p < 0.01 compared to control group mice