Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats

Table 5 Histomorphometrical analysis of the colon and remnant fecal pellets in the constipation rats induced by LP

Groups	Histomorphometry (at sacrifice)
Groups	Fecal pellet surface mucous thicknesses (μm)	Mucous producing cell numbers (cells/mm²)	Colon mucosa thicknesses (μm)
Control
Intact	62.28 ± 17.39	610.38 ± 140.52	523.25 ± 118.89
LP	14.42 ± 2.05^a	148.50 ± 46.34^a	214.56 ± 38.30^a
Reference
SP 5 mg/kg	101.83 ± 17.48^ac	482.25 ± 57.62^c	405.61 ± 51.15^bc
FBe treated as
300 mg/kg	76.09 ± 13.22^c	380.25 ± 70.14^ac	362.15 ± 56.27^ac
200 mg/kg	54.12 ± 12.84^c	308.13 ± 45.17^ac	314.98 ± 86.75^ac
100 mg/kg	26.68 ± 9.42^ac	274.88 ± 60.44^ac	273.14 ± 22.32^ac

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