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Table 4 Gastrointestinal charcoal transit ratio in the constipation rats induced by LP

From: Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats

Groups

Gastrointestinal motilities (during 30 min)

Total small intestine length (cm)

Length of charcoal meal transferred (cm)

Gastrointestinal charcoal transit ratio (%)

Control

 Intact

107.53 ± 7.38

77.45 ± 5.87

72.07 ± 3.52

 LP

106.60 ± 8.54

42.93 ± 10.89a

39.65 ± 10.50a

Reference

 SP 5 mg/kg

108.71 ± 9.61

57.10 ± 11.31ac

52.57 ± 9.58ac

FBe treated as

 300 mg/kg

107.99 ± 8.74

67.44 ± 10.91bc

63.19 ± 13.10c

 200 mg/kg

109.14 ± 9.88

60.98 ± 10.63ac

55.84 ± 8.18ac

 100 mg/kg

108.33 ± 6.11

55.90 ± 4.68ac

51.64 ± 3.91ad

  1. Values are expressed mean ± S.D. of eight rats
  2. FBe = Triple fermented barley extracts, test material
  3. SP = Sodium picosulfate
  4. LP = Loperamide
  5. Charcoal transit ratio (%) = [(Total small intestine length – Length of charcoal meal transferred)/Total small intestine length] × 100
  6. ap < 0.01 and b p < 0.05 as compared with intact control by LSD test
  7. cp < 0.01 and d p < 0.05 as compared with LP control by LSD test