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Table 3 Fecal parameters in the constipation rats induced by LP

From: Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats

Time/Index Groups Collected at 1 day before treatment for 24 h Collected from after 4th administration for 24 h
Pellet numbers = (numbers/rat) Wet-weights (g/rat) Dry-weights (g/rat) Water contents (%/rat) Pellet numbers (numbers/rat) Wet-weights (g/rat) Dry-weights (g/rat) Water contents (%/rat)
Control
 Intact 60.25 ± 12.43 9.72 ± 1.46 6.67 ± 1.57 32.06 ± 3.76 57.75 ± 11.67 9.71 ± 1.29 6.63 ± 1.23 32.16 ± 3.69
 LP 61.25 ± 12.52 9.65 ± 0.91 9.74 ± 0.92 30.33 ± 3.24 32.50 ± 6.21a 3.81 ± 0.75a 3.34 ± 0.58a 11.91 ± 4.04a
Reference
 SP 5 mg/kg 62.50 ± 13.21 10.37 ± 1.44 7.39 ± 1.55 29.38 ± 5.97 67.88 ± 11.34c 10.66 ± 1.35c 7.14 ± 1.10c 33.08 ± 5.68c
FBe treated as
 300 mg/kg 62.25 ± 11.18 9.61 ± 1.45 6.48 ± 1.48 33.10 ± 5.62 59.00 ± 11.64c 9.73 ± 1.37c 7.11 ± 1.05c 26.99 ± 2.71bc
 200 mg/kg 60.75 ± 16.59 9.96 ± 1.73 6.87 ± 1.84 31.90 ± 6.26 54.38 ± 10.93c 9.28 ± 1.30c 7.08 ± 0.94c 23.51 ± 5.18ac
 100 mg/kg 60.88 ± 13.65 10.10 ± 1.32 7.01 ± 1.66 31.43 ± 7.86 44.00 ± 7.69bd 8.21 ± 0.79bc 6.73 ± 0.57c 18.01 ± 2.77ac
  1. Values are expressed mean ± S.D. of eight rats
  2. FBe = Triple fermented barley extracts, test material
  3. SP = Sodium picosulfate
  4. LP = Loperamide
  5. To determine fecal dry weights, all collected fecal pellets were dried at 60 °C in a general dry oven for 24 h
  6. Fecal pellet water contents (%) = [(fecal wet-weight – fecal dry-weigh)/fecal wet-weight] × 100
  7. ap < 0.01 and b p < 0.05 as compared with intact control by LSD test
  8. cp < 0.01 and d p < 0.05 as compared with LP control by LSD test