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Table 2 Body weight gains in the constipation rats induced by LP

From: Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats

Time/Index Groups

Body weights at

Body weight gains [B-A]

1 day before first treatment

First treatment day* [A]

Last (6th) treatment day* [B]

Control

 Intact

261.75 ± 14.51

231.50 ± 17.25

262.13 ± 17.52

30.63 ± 4.21

 LP

262.25 ± 13.23

233.13 ± 13.08

263.25 ± 15.48

30.13 ± 7.49

Reference

 SP 5 mg/kg

262.50 ± 12.95

234.25 ± 13.50

238.38 ± 12.82ab

4.13 ± 3.83ab

FBe treated as

 300 mg/kg

261.88 ± 12.77

232.50 ± 11.20

264.13 ± 15.64

31.63 ± 6.74

 200 mg/kg

262.13 ± 10.26

234.38 ± 10.51

263.00 ± 14.11

28.63 ± 9.01

 100 mg/kg

262.50 ± 16.86

233.00 ± 16.07

265.88 ± 10.19

32.88 ± 6.58

  1. Values are expressed mean ± S.D. of eight rats, g
  2. FBe = Triple fermented barley extracts, test material
  3. SP = Sodium picosulfate
  4. LP = Loperamide
  5. *Overnight fasted
  6. ap < 0.01 as compared with intact control by LSD test
  7. bp < 0.01 as compared with LP control by LSD test
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