Liver function parameters | GI (Control) | GII (CCl4-only) | GIII (CCl4+ SSEE 100 mg) | GIV (CCl4+ SSEE 200 mg) | GV (CCl4+ Silymarin 10 mg) |
---|---|---|---|---|---|
AST (U/L) | 107.45 ± 5.31 | 294.83 ± 8.33*** | 288.50 ± 7.36 b | 262.50 ± 6.87b | 136.66 ± 6.00**b |
ALT (U/L) | 28.83 ± 2.20 | 230.83 ± 9.62***a | 198.16 ± 7.12*b | 159.50 ± 9.17***b | 85.66 ± 4.31***b |
ALP (U/L) | 321.66 ± 13.8 | 515.16 ± 13.7***a | 479.00 ± 6.12* b | 436.33 ± 12.31**b | 396.33 ± 7.62***b |
GGT (U/L) | 4.06 ± 0.32 | 12.85 ± 0.98***a | 11.38 ± 0.49b | 9.46 ± 0.32**b | 5.58 ± 0.28***b |
BIL (mg/dL) | 0.54 ± 0.01 | 2.16 ± 0.08***a | 1.81 ± 0.05*b | 1.57 ± 0.06***b | 1.06 ± 0.06***b |
TC (mg/dL) | 109.83 ± 3.9 | 206.00 ± 4.53***a | 179.50 ± 6.63**b | 168.83 ± 6.16*** | 147.66 ± 4.88***b |
TG (mg/dL) | 59.01 ± 2.74 | 151.16 ± 4.61***a | 119.33 ± 3.8***b | 96.81 ± 3.75***b | 110.16 ± 5.26***b |
HDL (mg/dL) | 55.18 ± 2.40 | 25.25 ± 1.79*** | 26.53 ± 1.22b | 36.28 ± 1.78**b | 40.41 ± 2.97**b |
LDL (mg/dL) | 42.84 ± 3.22 | 149.51 ± 4.28***a | 130.10 ± 7.50*b | 113.18 ± 7.60**b | 85.21 ± 5.98***b |
VLDL (mg/dL) | 11.80 ± 0.54 | 30.23 ± 0.92***a | 23.86 ± 0.76***b | 19.36 ± 0.75***b | 22.02 ± 1.05***b |
TP (g/L) | 113.76 ± 2.8 | 49.11 ± 1.82***a | 53.88 ± 2.81b | 71.452.64***b | 91.81 ± 4.08***b |
MDA (nmol/g) | 0.50 ± 0.02 | 4.82 ± 0.29***a | 4.47 ± 0.23b | 2.75 ± 0.1***b | 1.37 ± 0.16***b |
NP-SH (nmol/g) | 7.39 ± 0.53 | 3.86 ± 0.44***a | 5.79 ± 0.35**b | 5.93 ± 0.31**b | 6.52 ± 0.31***b |