Fig. 1From: Modulation of neurological pathways by Salvia officinalis and its dependence on manufacturing process and plant parts usedCompetition binding at several receptors. Competition binding of Salvia officinalis extract at the human adrenergic alpha 2A receptor expressed in Chem-1 cells (a), the muscarinic M3 receptor expressed in CHO cells (b), the human μ-opioid receptor expressed in CHO-K1 cells (c), the human serotonin transporter expressed in HEK293 cells (d, Salvia off. tincture), the human serotonin 5-HT1A receptor expressed in HEK293-EBNA cells (e), and the human serotonin 5-HT2B receptor expressed in CHO-K1 cells (f). Summary curves over 2–3 independent experiments performed in duplicate (mean specific binding ± S.E.M.). The calculated IC50 values are indicated above the figure. The horizontal dashed line marks 50% specific bindingBack to article page