Fig. 7

Effects of MESZS on the mRNA expressions of amygdaloid (a) N/OFQ and (b) NOP during EtOHW. Immediately after the behavioral test, the mRNA levels of N/OFQ and NOP in the CeA were evaluated using qPCR analysis. All data are expressed as a mean ± SEM (n = 5). S: saline, DW: distilled water, EtOH: ethanol, MESZS: methanol extract of Semen Ziziphi Spinosae, MESZS180: 180 mg/kg/d MESZS. ^### p < 0.001 vs. S/DW group; ^$ p < 0.05, ^$$ p < 0.01 vs. EtOH/DW group; ^@@@ p < 0.001 vs. EtOH/MESZS180 group (one-way ANOVA followed by Newman-Keuls post hoc test)