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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

Fig. 4

Effects of MESZS on plasma CORT concentrations during EtOHW. Withdrawal from chronic EtOH administration increased plasma CORT levels in rats, which was prevented by MESZS treatment. All data are expressed as a mean ± SEM (n = 8). S: saline, DW: distilled water, EtOH: ethanol, CORT: corticosterone; MESZS: methanol extract of Semen Ziziphi Spinosae, MESZS60: 60 mg/kg/d MESZS, MESZS180: 180 mg/kg/d MESZS. ### p < 0.001 vs. S/DW group; $$$ p < 0.001 vs. EtOH/DW group (one-way ANOVA followed by Newman-Keuls post hoc test)

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