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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

Fig. 3

Effects of MESZS on the behavioral changes of rats in the elevated plus maze test. All data are expressed as a mean ± SEM (n = 8). (a) The total number of entries into (open and closed) arms of EPM by rats. (b) Percentage of numbers of entries into open arms. (c) Percentage of time spent in open arms. S: saline, DW: distilled water, MESZS: methanol extract of Semen Ziziphi Spinosae, MESZS60: 60 mg/kg/d MESZS, MESZS180: 180 mg/kg/d MESZS. ## p < 0.01, ### p < 0.001 vs. S/DW group; $ p < 0.05, $$ p < 0.01, $$$ p < 0.001 vs. EtOH/DW group; @ p < 0.05, vs. EtOH/MESZS180 group (one-way ANOVA followed by Newman-Keuls post hoc test)

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