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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

Fig. 1

(a) HPLC profile of MESZS, which includes magnoflorine, spinosin, and 6′′′-feruloyl spinosin. (b) HPLC profile of MESZS, which includes Jujuboside A. (c) Time schedule for ethanol withdrawal (EtOHW). Rats were given with EtOH (2 g/kg, dissolved in saline, i.p., once a day) for 28 consecutive days followed by 3 d of withdrawal and then evaluated for behavioral and biochemical changes. During the EtOHW, the rats were administered with MESZS (60 or 180 mg/kg/d, three times). MESZS: methanol extract of Semen Ziziphi Spinosae; OF: open field; EPM: elevated plus maze

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