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Table 2 The cell cycle distribution on BxPC-3 and Panc-1 cell line after 12 h of elemene treatment

From: Anti-tumor effect and mechanistic study of elemene on pancreatic carcinoma

Group

Dosage (μg/mL)

BxPC-3

Panc-1

G0/G1

S

G2/M

G0/G1

S

G2/M

Control

75.8 ± 1.9

18.6 ± 0.8

5.6 ± 0.05

86.1 ± 1.2

6.3 ± 0.07

7.6 ± 0.04

Elemene

15

61.2 ± 1.3*

34.6 ± 0.7*

4.2 ± 0.03*

78.3 ± 0.9*

15.2 ± 0.6*

6.5 ± 0.03*

30

47.7 ± 0.9**

49.1 ± 0.6**

3.2 ± 0.02**

60.1 ± 0.7**

34.8 ± 0.9**

5.1 ± 0.02**

60

30.6 ± 0.5**

66.7 ± 0.8**

2.7 ± 0.09**

46.3 ± 0.8**

50.1 ± 1.1**

3.6 ± 0.04**

  1. Data are expressed as mean ± SD for each group. *P < 0.05, **P < 0.01 vs control group