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Table 2 The cell cycle distribution on BxPC-3 and Panc-1 cell line after 12 h of elemene treatment

From: Anti-tumor effect and mechanistic study of elemene on pancreatic carcinoma

Group Dosage (μg/mL) BxPC-3 Panc-1
G0/G1 S G2/M G0/G1 S G2/M
Control 75.8 ± 1.9 18.6 ± 0.8 5.6 ± 0.05 86.1 ± 1.2 6.3 ± 0.07 7.6 ± 0.04
Elemene 15 61.2 ± 1.3* 34.6 ± 0.7* 4.2 ± 0.03* 78.3 ± 0.9* 15.2 ± 0.6* 6.5 ± 0.03*
30 47.7 ± 0.9** 49.1 ± 0.6** 3.2 ± 0.02** 60.1 ± 0.7** 34.8 ± 0.9** 5.1 ± 0.02**
60 30.6 ± 0.5** 66.7 ± 0.8** 2.7 ± 0.09** 46.3 ± 0.8** 50.1 ± 1.1** 3.6 ± 0.04**
  1. Data are expressed as mean ± SD for each group. *P < 0.05, **P < 0.01 vs control group