The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice

Table 2 Effects of AqE on cardiac function in L-NAME induced hypertensive mice (mean ± SD, n = 10)

Group	LVSP(mmHg)	LVEDP(mmHg)	+dp/dt_max(mmHg/s)	-dp/dt_max(mmHg/s)
Control	89.25 ± 13.02	−0.31 ± 1.79	4616.92 ± 713.09	− 3855.15 ± 659.27
Model	114.5 ± 15.16^**	−1.15 ± 6.09	5487.19 ± 674.56^*	− 4767.96 ± 934.34^*
L-NAME+AqE	116.76 ± 9.96	−0.09 ± 8.25	4777.74 ± 797.27	− 3502.52 ± 976.41^##
L-NAME+XJEK	111.41 ± 15.36	−1.18 ± 5.13	4873.61 ± 1113.51	− 3849.29 ± 1039.70
L-NAME+Fosinopril	100.56 ± 21.72^#	0.37 ± 5.32	4618.46 ± 339.42^##	− 3457.26 ± 736.12^##

LVSP left ventricular systolic pressure, LVEDP left ventricular end-diastolic pressure, +dp/dt_max maximal rate of left ventricular systolic pressure, −dp/dt_max maximal rate of left ventricular diastolic pressure. ^*P < 0.05, ^**P < 0.01 vs control; ^#P < 0.05, ^##P < 0.01 vs model

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