Skip to main content

Table 3 Neem soap minimum inhibitory and minimum bactericidal concentrations (MIC and MBC)

From: Inhibitory effects of Azadirachta indica secondary metabolites formulated cosmetics on some infectious pathogens and oxidative stress radicals

Test Pathogens

Neem Soap

Controls

NMS

NMLS a

NMSBS b

NMLSBS c

Ciprofloxacin d

Water e

MIC

mg /mL

MBC

mg / mL

MIC

mg/mL

MBC

mg /mL

MIC

mg /mL

MBC

mg /mL

MIC

mg /mL

MBC

mg/mL

MIC

mg/mL

MBC

mg/mL

MIC

500 μL

L. ivanovii

0.400 ± 0.03

0.800 ± 0.01 VG

0.200 ± 0.03

0.400 ± 0.01 NG

0.200 ± 0.02

0.400 ± 0.01 NG

0.012 ± 0.002

0.025 ± 0.001 NG

0.012 ± 0.001

0.05 ± 0.01 NG

VG

S. aureus

0.800 ± 0.02

0.800 ± 0.10 VG

0.400 ± 0.04

0.800 ± 0.01 NG

0.400 ± 0.04

0.400 ± 0.03 NG

0.200 ± 0.03

0.200 ± 0.02 NG

0.050 ± 0.001

0.050 ± 0.04 NG

VG

M.smegmatis

0.400 ± 0.04

0.800 ± 0.04 VG

0.400 ± 0.12

0.400 ± 0.03 VG

0.400 ± 0.04

0.400 ± 0.11 NG

0.200 ± 0.04

0.400 ± 0.02 NG

0.050 ± 0.02

0.100 ± 0.02 NG

V G

E. coli 180*

0.800 ± 0.03

0.800 ± 0.03 VG

0.800 ± 0.11

0.800 ± 0.04 VG

0.400 ± 0.02

0.800 ± 0.03 NG

0.400 ± 0.01

0.800 ± 0.01 NG

0.050 ± 0.01

0.050 ± 0.02 NG

V G

V.paraheamolyticues *

0.400 ± 0.01

0.800 ± 0.03 VG

0.400 ± 0.03

0.800 ± 0.03 NG

0.400 ± 0.02

0.800 ± 0.03 NG

0.200 ± 0.02

0.400 ± 0.01 NG

0.050 ± 0.01

0.050 ± 0.01NG

V G

E. cloacae

0.400 ± 0. 01

0.800 ± 0.04 VG

0.200 ± 0.01

0.400 ± 0.02 NG

0.025 ± 0.020

0.100 ± 0.010 NG

0.025 ± 0.020

0.200 ± 0.010 NG

0.012 ± 0.010

0.012 ± 0.001 NG

V G

S. uberis

0.800 ± 0.02

0.800 ± 0.03 VG

0.40 ± 0.01

0.800 ± 0.04 VG

0.40 ± 0.03

0.800 ± 0.03 NG

0.40 ± 0.00

0.800 ± 0.01 NG

0.050 ± 0.01

0.050 ± 0.01 NG

ND

  1. NMS= neem soap without neem essential oil
  2. aNMLS = neem soap with leaf EO
  3. bNMSBS = neem soap with neem stem-bark EO
  4. cNMLSBS = neem soap with the leaf and stem-bark EO
  5. dciprofloxacin = positive control
  6. eWater = negative control
  7. * confirmed bacterial resistant strains, VG = Visible growth (bacteriostatic), NG = No visible growth (bactericidal) on solid agar plate, ND = Not determined