Table 1 Checkerboard assay of GEN, AMK, KAN, AMP, VAN, TET and OBN against S. aureus
From: Ouabain potentiates the antimicrobial activity of aminoglycosides against Staphylococcus aureus
Antimicrobial agents | MIC of each agent (μg/mL) |  |  | ||
|---|---|---|---|---|---|
alone | Comb | FIC | FICI | Outcome | |
GEN | 4 | 0.25 | 0.0625 | Â | Â |
OBN | 32000 | 1000 | 0.03125 | 0.0937 | Syn |
AMK | 4 | 0.5 | 0.125 | Â | Â |
OBN | 32000 | 1000 | 0.03125 | 0.1562 | Syn |
KAN | 16 | 1 | 0.0625 | Â | Â |
OBN | 32000 | 2000 | 0.0625 | 0.125 | Syn |
AMP | 0.5 | 0.25 | 0.5 | Â | Â |
OBN | 32000 | 8000 | 0.25 | 0.75 | NI |
VAN | 1 | 0.25 | 0.25 | Â | Â |
OBN | 32000 | 16000 | 0.5 | 0.75 | NI |
TET | 2 | 0.5 | 0.25 | Â | Â |
OBN | 32000 | 8000 | 0.25 | 0.5 | NI |